Scientist II Job at F. Hoffmann-La Roche Ltd, Pleasanton, CA

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  • F. Hoffmann-La Roche Ltd
  • Pleasanton, CA

Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

The Opportunity

We are seeking a highly motivated and skilled Scientist to join our dynamic NGS Library Preparation and Target Enrichment team. The successful candidate will play a crucial role in the execution of sample preparation workflows, contributing to our ongoing research and development efforts. This position requires a strong foundation in molecular biology techniques, hands-on experience with relevant instrumentation, and the ability to thrive in a fast-paced, collaborative environment.

In this role, you are:

  • Preparing NGS libraries from various sample types, demonstrating proficiency in multiple library construction methods.
  • Extracting DNA and RNA from diverse biological samples, optimizing protocols for yield and purity, and accurately quantifying nucleic acids using instruments like Qubit and NanoDrop.
  • Operating, maintaining, and troubleshooting sequencing platforms for routine sequencing runs, and utilizing quality control methods such as Agilent TapeStation for nucleic acids and NGS libraries.
  • Maintaining detailed experimental records, including laboratory notebooks and digital data, while analyzing and interpreting experimental results for report generation and presentations.
  • Collaborating with team members on experimental design, troubleshooting, and data analysis, while adhering to laboratory safety guidelines and maintaining an organized workspace.

Who You Are

  • Bachelor's or Master's degree in Molecular Biology, Genetics, Biochemistry, or a related scientific field with 2-4 years of relevant laboratory experience, preferably in an industry setting.
  • Demonstrated hands-on experience with NGS library preparation protocols (e.g., DNA-seq, RNA-seq, exome sequencing).
  • Proficiency in standard molecular biology techniques, including PCR, nucleic acid extraction, and purification.

Behaviors, competencies, and qualities of the ideal applicant.

  • Solid experience with DNA QC instruments such as Qubit, Tapestation, Nanodrop, etc.
  • Strong critical thinking and problem-solving skills with a meticulous attention to detail. Excellent communication and interpersonal skills, with a proven ability to work effectively within a team.
  • Highly organized, self-motivated, and able to manage time efficiently to meet project timelines. Ability to work independently and as part of a team in a fast-paced, deadline-driven environment.

Relocation benefits are not offered for this job.

The expected salary range for this position in Pleasanton is $79,000.00 - $109,365.00 USD annually.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.


Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

Job Tags

Local area, Relocation package,

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